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Drug metabolism
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161	PDF Document Add to Reading List Source URL: media.wiley.com Language: English - Date: 2009-01-27 05:06:18 Hepatology Flavors Solvents Xenobiotic metabolism Benzoic acid Drug metabolism Toluene toxicity Hippuric acid Biotransformation Chemistry Metabolism Pharmacology
162	1 TE Chandra Prakash and Alfin D. N. Vaz RI Add to Reading List Source URL: media.wiley.com Language: English - Date: 2008-10-21 05:02:06 Medicine CYP3A4 Drug metabolism CYP3A CYP2D6 Metabolism CYP2A6 Xenobiotic CYP1B1 Cytochrome P450 Biology Chemistry
163	PDF Document Add to Reading List Source URL: media.wiley.com Language: English - Date: 2007-10-05 12:39:46 Medicinal chemistry Pharmacokinetics Pharmacy Clinical research Biotransformation Xenobiotic metabolism Drug discovery Aspirin Toxicology Pharmaceutical sciences Pharmacology Chemistry
164 $Pharmacokinetics / Metabolism / Pharmacy / Medicinal chemistry / Microsome / Cytochrome P450 / S9 fraction / Hepatocyte / CYP3A4 / Pharmaceutical sciences / Pharmacology / Biology$	Lee xen0021.tex V2[removed]Metabolic stability screen in drug discovery Add to Reading List Source URL: media.wiley.com Language: English - Date: 2013-12-07 04:35:54 Pharmacokinetics Metabolism Pharmacy Medicinal chemistry Microsome Cytochrome P450 S9 fraction Hepatocyte CYP3A4 Pharmaceutical sciences Pharmacology Biology
165	Microsoft PowerPoint - ch-1-Figure 1.ppt [Read-Only] Add to Reading List Source URL: media.wiley.com Language: English - Date: 2013-08-23 16:16:22 Medicinal chemistry Pharmacy Metabolism ADME Bioanalysis Biotransformation Drug metabolism Toxicology Drug discovery Pharmaceutical sciences Pharmacology Pharmacokinetics
166	PDF Document Add to Reading List Source URL: www.wiley-vch.de Language: English - Date: 2012-02-09 21:04:42 Hemoproteins Metabolism Antioxidants Enzymes Toxicology Cytochrome P450 Peroxidase Drug metabolism Glutathione Chemistry Biology Biochemistry
167	FOOD AND DRUG ADMINISTRATION (FDA) Center for Drug Evaluation and Research (CDER) Arthritis Advisory Committee (AAC) Meeting FDA White Oak Campus, Building 31, The Great Room (Rm[removed]White Oak Conference Center, Silve Add to Reading List Source URL: www.fda.gov Language: English Inborn errors of purine-pyrimidine metabolism Arthritis Gout Rheumatology Colchicine Rilonacept Non-steroidal anti-inflammatory drug Regeneron Febuxostat Chemistry Organic chemistry Uric acid
168	Figure 3. General Scheme of Model-Based Prediction: The Investigational Drug (and Metabolite Present at ≥25% of Parent Drug AUC) as an Interacting Drug of CYP Enzymes CYP induction CYP inhibition (reversible and time-d Add to Reading List Source URL: www.fda.gov Language: English Biology Enzymes Pharmacokinetics Enzyme inhibitors Pharmacology Enzyme Microsome Physiologically based pharmacokinetic modelling Chemistry Metabolism Pharmaceutical sciences
169	Figure 1. Metabolism-Based Drug-Drug Interaction Studies — Decision Tree Conduct In Vitro Metabolism and Drug-Drug Interaction Studies in Human Tissuesa - Phase I enzymes: CYP 1A2, 2B6, 2C8, 2C9, 2C19, 2D6, 3A, others Add to Reading List Source URL: www.fda.gov Language: English Biomolecules Catalysis Pharmacokinetics Metabolism Enzyme In vitro In vivo Cytochrome P450 Simcyp Simulator Chemistry Pharmaceutical sciences Pharmacology
170	FOOD AND DRUG ADMINISTRATION (FDA) Center for Drug Evaluation and Research (CDER) Arthritis Advisory Committee (AAC) Meeting FDA White Oak Campus, Building 31, The Great Room (Rm[removed]White Oak Conference Center, Silve Add to Reading List Source URL: www.fda.gov Language: English Inborn errors of purine-pyrimidine metabolism Arthritis Gout Rheumatology Colchicine Rilonacept Non-steroidal anti-inflammatory drug Regeneron Febuxostat Chemistry Organic chemistry Uric acid

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